The simple answer is no. Misa doesn't die in the anime itself. ... Misa's last scene is at the end of the final episode of Death Note.
How old was Light Yagami died?
Light Yagami
Born:
February 28 1986 (1989 in the anime)
Death Date:
1/28/2010 (2013 in the anime)
Age:
17 (at series beginning)23 (at series end)
Gender:
Male
Did light kill Misa?
When she regains her memories by Rem telling her Rem states that if Light tries to harm Misa in anyway she will kill him. Misa responds "I don't exactly want to be loved by a Shinigami, and if Light died I couldn't live on without him. There's no way Light would kill Misa-Misa. And why would you go so far for me.".
What happened to Misa Death Note?
Since it is in the nature of a Death Note user to "suffer misfortune", Misa falls into despair after someone "like Matsuda" "probably let it slip" that Light died. When she regains her memories by Rem telling her Rem states that if Light tries to harm Misa in anyway she will kill him.
Does Misa die Death Note?
Misa then goes outside, having written her own name and the circumstances of her death on a scrap of Death Note paper. As written, she dies on December 18th at 2:40 pm "in the arms of Light Yagami .". It is also revealed in the fourth film that Light had a child who would be nine years old.
How does Misa Amane die?
At the end of the anime, shortly after Light's death, Misa is seen standing on the ledge of a tall building alone. Although it is not shown, it is theorized that she committed suicide following Light's death.
